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This presentation explores the significance of immune-related adverse events (irAEs) in rheumatology, detailing their epidemiology, recognition, and management. It covers the evolution of immune checkpoint inhibitors (ICIs) from ipilimumab, the spectrum of rheumatic phenotypes, and the importance of systematic diagnosis. Emphasis is placed on grading toxicity, treating severe cases, and balancing immunosuppression with antitumour efficacy. Key topics include the identification of...