Advancing Treatment in TP53-Mutated MDS/AML

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This lecture provides an in-depth exploration of TP53-mutated myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML), focusing on the biological implications of TP53 mutations, their impact on prognosis, and current therapeutic responses. The session covers mutation types, prognostic factors, and immune dysregulation before delving into existing therapies and their limitations. Highlighting the significance of emerging therapeutic approaches, including immunotherapies and cellular...