Innovative Nanorobots for Targeted Thrombolysis

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This project focuses on the innovative design of systemic-to-local nanorobots aimed at enhancing thrombolysis. It addresses the limitations of current treatments by utilizing a p-Fe3O4@PVP CNC structure for magnetic delivery and tPA loading. The study evaluates targeted thrombolysis through magnetic propulsion and mechanical-enzymatic synergy, demonstrating effective in vitro results and successful recanalization in rat models. Additionally, it examines the biodegradation, safety, and...