The Role of H3K56 in Genome Stability and Cancer
The Role of H3K56 in Genome Stability and Cancer
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This project aims to explore the role of H3K56 in DNA replication, hypothesizing that chromatin configuration aids this process. Understanding chromatin's function can offer critical insights into cancer treatment, as disruptions in chromatin are linked to cancer. Our research targets key gaps by studying H3K56's influence on origin licensing, evaluating PCNA’s role in fork progression, and assessing cellular stress and stability. This innovative approach, involving novel biochemical...