High-Throughput Drug Safety Analysis in CKD Older Adults

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This research focuses on drug-safety analysis in individuals with chronic kidney disease (CKD), emphasizing older populations. Utilizing Ontario healthcare databases, the study examines drug effects through stratification by eGFR levels and employs robust statistical methods, including propensity score matching, for outcome validation. Insights from dose-response analyses and case studies of significant drug impacts enhance interpretation of statistical signals, aiming to provide actionable...