Advancements in Clinical Management of Primary CNS Lymphoma

Explore PCNSL within CNS disorders by examining its clinical impact, epidemiology, and anatomical context. This presentation reviews diagnostic strategies—from MRI and biopsy to CSF evaluations—and standard treatment protocols including high-dose methotrexate, radiation, and stem cell transplantation. It also covers novel targeted therapies addressing B-cell receptor mutations with agents like ibrutinib and lenalidomide, and discusses the challenges of relapse and limited survival outcomes,...