Phosphorylation and Cancer: New Therapeutic Insights
Phosphorylation and Cancer: New Therapeutic Insights
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This project explores the role of phosphorylation in cancer control, focusing on key proteins like SHARPIN, CIP2A, and PP2A. It defines essential concepts such as protein phosphorylation and its impact on cancer hallmarks. The study highlights SHARPIN's role in invasion and metastasis through specific phosphorylation sites and interactions, supported by zebrafish models. Additionally, it discusses the therapeutic potential of targeting CIP2A and PP2A in ovarian cancer, emphasizing the...