Ki-67 as a Prognostic Marker in Oral Lesions

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This research study investigates the role of Ki-67 as a proliferation biomarker in Oral Epithelial Dysplasia (OED) and Oral Squamous Cell Carcinoma (OSCC). By employing immunohistochemistry on 70 formalin-fixed samples, the study identified a significant correlation between Ki-67 expression and disease severity, from the basal layers of Normal Oral Epithelium (NOE) to advanced OSCC. The findings suggest Ki-67's potential as a prognostic marker, aiding in both diagnosis and therapeutic...