article research paper on evidence based review on efficacy of oral corticosteroid or systematic analysis of monteleukast on acutepediatric wheezing and asthma excerbation

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This review addresses the clinical question of the effectiveness of oral corticosteroids (OCS) versus placebo in managing preschool wheeze, which poses a significant acute-care burden. The results indicate no significant overall admission effect, with a notable risk increase in outpatient settings when OCS is used. The findings suggest that broad OCS use is not supported by evidence, although potential benefits may exist in acute care scenarios, particularly influenced by viral triggers....