as A good SLIDE PLASE mAKE A pRESENTATION ON C-kANT 4MG **Slide 1 Content** * **Header:** * C-Kast® (Montelukast Sodium) * Tablets 10 mg / 5 mg (Chewable) * 24-hours relief against Asthma and Allergic Rhinitis * **Global Recommendation:** * **GINA 2024:** Recommends leukotriene receptor antagonist (montelukast) as an alternative controller option in steps 2 for the asthma patients 12+ years and as an add-on therapy. * **ARIA:** Guidelines recommends the use of LTRA in mild to moderate severe intermittent and persistent allergic rhinitis symptoms. * **NAEPP:** Guidelines recommends use of LTRA as alternative option in step 3 & 4 in persistent asthma. * **Clinical Findings:** * A study performed in 681 patients aged over 15 years showed that **C-Kast®** (montelukast 10 mg once daily) **REDUCED**: * Nocturnal Awakening * Daytime Asthma Symptoms * β-agonist use * Eosinophil Counts * In a trial carried out in children aged 6 to 14 with mild to moderate asthma, **C-Kast®** (montelukast 5 mg once daily) increased morning $\text{FEV}_1$ compared with placebo. * Significant improvements in all quality of life domains (**Symptoms**, **Activity**, **Environment**, **Emotion**) occurred with **C-Kast®** (montelukast) treatment. --- **Slide 2 Content** * **Header:** * C-Kast® (Montelukast Sodium) | 10 mg & 5 mg (Chewable) * 24-hours relief against Asthma and Allergic Rhinitis * **Clinical Effectiveness & Safety:** * Clinical effectiveness and safety of montelukast in asthma. * LTRAs can be used as a monotherapy or as an add-on therapy in addition to ICS. They may be an effective alternative in asthma control and safe even with long-term usage. The advantages of LTRAs include low risks of side effects and rapid onset of action and achievement of peak effect. * **Efficacy Metrics:** * Highly Effective in improving quality of life of Adults with Asthma & Allergic Rhinitis. * Treatment with 10 mg montelukast **86.5%** ($n=4547$) of patients reported a strong or marked improvement in day-time asthma symptoms and **88.5%** ($n=4367$) reported improvement in night-time symptoms. * High proportion of patients had a strong or marked improvement in all symptoms of allergic rhinitis: * **78%** Burning Eyes * **78%** Watery Eyes * **79%** Nasal Congestion * **81%** Rhinorrhea * **84%** Sneezing, Itching * **Branding:** Chiesi | Tutti Frutti flavor callout --- **Slide 3 Content** * **Header/Tagline:** * Add ON to * Keep ON * **Product Details:** * C-Kast® (Montelukast Sodium) * 5 mg & 10 mg Tablets * Tutti Frutti flavor * Chiesi logo