GLI1 and MAPK Roles in Aggressive Ameloblastoma

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This presentation explores the genetic mutations in ameloblastoma, focusing on the role of the SHH pathway and GLI1 in tumor progression and aggression. Utilizing mutation analysis and statistical techniques, findings reveal BRAF mutations and GLI1 overexpression with potential implications for tumor recurrence and targeted therapies. Immunohistochemistry highlights a keratin link to GLI1, emphasizing its role in tumor behavior. Discussion revolves around MAPK and SHH pathways, underscoring...