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ANCA-Associated Vasculitis (AAV) is an autoimmune disease impacting blood vessels, notably including GPA and MPA subtypes. This chronic condition, marked by significant morbidity and potential organ damage, is strongly linked to ANCA markers. Avacopan, an oral C5a receptor antagonist, offers promising treatment benefits by targeting inflammation with reduced glucocorticoid toxicity. The Phase 3 ADVOCATE trial highlights its efficacy, especially when combined with CYC induction, showing...