SV40: Implications for Human Health and Cancer

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This overview explores the biology and historical context of SV40, including its discovery and implications from vaccine contamination. It discusses human susceptibility, detailing infection cases, exposure cohorts, and immune responses, particularly in immunocompromised individuals. Additionally, it examines the potential links between SV40 and various cancers, assessing tumor associations and the distinction between authentic viral presence and contamination, while emphasizing the need for...