Advancing RNA Delivery Efficiency with Chemical Modifications

This presentation explores RNA's critical role in gene expression, gene silencing mechanisms, and advancements in RNA-based therapeutics. It delves into mRNA techniques in vaccine development, production challenges, and strategies for efficient RNA delivery, including lipid nanoparticles and chemical modifications. Key focus is placed on enhancing RNA uptake via innovative methods, such as cholesterol alteration and assembly constructs, supported by evaluations of siRNA and ASO uptake in...