Cholesterol Metabolism Disruption by HBV Mutations

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This presentation provides an in-depth analysis of cholesterol metabolism disruptions in Hepatitis B Virus (HBV) mutants, focusing on key mutations such as A1762T/G1764A and G1896A. Using a cohort of 108 CHB patients, researchers employed advanced proteomics and metabolomics techniques to link these genetic variations with severe liver conditions and immune evasion strategies. Significant findings include cholesterol pathway dysregulation and the identification of six potential biomarkers for...