Clinical correlation of arrhythmias with pharmacology mechanism of action of anti-arrhythmic drugs

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This presentation delves into the clinical framework for managing arrhythmias, emphasizing the mapping of ECG phenotypes to electrophysiologic substrates and the selection of therapies based on clinical context. It explores the mechanistic architecture of anti-arrhythmic drugs, detailing sodium-channel blockade and the roles of autonomic and potassium/calcium-channel targets. The discussion includes drug selection for common arrhythmias, safety monitoring, and the potential for proarrhythmia....