Metagenomics in Neonatal Sepsis Diagnosis

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This presentation examines the clinical role of metagenomic next-generation sequencing (mNGS) in neonatal sepsis, addressing critical diagnostic gaps where conventional methods fall short. Drawing on a large retrospective cohort, it highlights mNGS’s superior sensitivity, broad pathogen detection, and value in complex and immunocompromised cases, while maintaining acceptable specificity. Real-world performance across sample types and its impact on clinical decision-making are discussed,...