HELLP Syndrome & Microangiopathy in Pregnancy

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This lecture delves into the complexities of thrombotic microangiopathies (TMAs) during pregnancy, focusing on HELLP syndrome, its overlapping conditions, and diagnostic challenges. We will explore how HELLP, atypical hemolytic uremic syndrome (aHUS), and thrombotic thrombocytopenic purpura (TTP) differ, emphasizing genetic, autoimmune aspects, and essential laboratory evaluations. We'll examine the role of ADAMTS13, complement testing, and timely diagnosis. Management strategies, including...