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This lecture explores CNS infection imaging, emphasizing the role of radiology using CT and MRI techniques. It covers general imaging approaches, highlights features of diffuse infections like meningitis and encephalitis, and discusses focal infections such as abscesses and empyemas. Key insights include the use of advanced imaging methods like DWI and FLAIR for accurate diagnosis, and the identification of specific conditions like HSV encephalitis and tuberculosis-related basilar meningitis.