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This presentation explores the significance of quality-of-life metrics in healthcare, analyzing tools like EORTC QLQ-C30 and FACT-O. It discusses recent patient-quality studies, highlighting findings such as minimal differences (SMD: -0.10) and low-quality evidence (GRADE). The analysis emphasizes key factors like low heterogeneity (I² = 15%) and temporary impacts on quality, generally resolving within six months. Confidence intervals' critical role in interpreting data is also examined....