Managing Severe Perianal Crohn’s: Biologic Strategies

This presentation explores the management of a 28-year-old patient with ileocolonic Crohn's disease, presenting severe symptoms including nocturnal diarrhoea, rectal bleeding, and dehydration. Diagnostics such as elevated CRP, ESR, and imaging confirmed fistulas and deep ulcerations. Treatment options include infliximab and adalimumab, with emphasis on optimizing therapy. Emerging approaches like guselkumab and dual biologics reflect advancements in severe case management, offering hope for...