please make diagramatic slides of pathogenesis of coagulopathy in apml.. just diagrams with explanation in pdf
please make diagramatic slides of pathogenesis of coagulopathy in apml.. just diagrams with explanation in pdf
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This overview addresses APML coagulopathy, highlighting the role of abnormal promyelocytes in DIC and the procoagulant signals released by APL cells that heighten bleeding risks. It discusses the molecular triggers leading to clinical bleeding, including tissue factor's activation of thrombin and the consumption of platelets and fibrinogen. A diagrammatic clinical response is outlined, emphasizing the importance of mapping bleeding and thrombosis, monitoring key laboratory parameters, and the...