Molecular Biomarkers in Axial Spondyloarthritis

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This study explores Axial Spondyloarthritis (axSpA), focusing on chronic inflammation affecting the spine and sacroiliac joints. It aims to identify gene clusters and biomarkers linked to disease progression and severity. Involving 144 patients, the research utilized RNA sequencing and serum proteomics to uncover predictive biomarker sets through machine learning. Key findings reveal distinct molecular clusters associated with varying disease activity and structural damage. The study...