Fusobacterium Nucleatum's Role in TNBC Chemoresistance

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This study addresses the clinical need for understanding triple-negative breast cancer (TNBC) and its reliance on chemotherapy, particularly focusing on the role of F. nucleatum in chemoresistance. It explores mechanisms of resistance, drawing on colorectal cancer (CRC) evidence and identifying gaps in TNBC knowledge. Utilizing a 4T1 mouse model, the research tests antibiotic treatments and transpapillary delivery methods, aiming to uncover outcomes that could significantly impact therapeutic...