Evaluating Cefazolin for CNS Infections

Exploring CNS drug delivery, this scientific teaching session covers the physiology of the brain barriers, comparing the Blood-Brain and Blood-CSF barriers. It delves into mechanisms by which drugs penetrate the CNS, pathogens in neurological infections like meningitis, and antibiotic options. A highlight is the debated role of cefazolin, supported by analysis and the latest 2025 Monte Carlo simulation, offering evidence-based insights for optimizing antibiotic use in CNS infections.