Impact of HDR Therapy on Cytokines and EVs in Tumor Reduction

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This presentation delves into cytokine changes following High-Dose-Rate (HDR) therapy, highlighting significant correlations between cytokines and tumor reduction. Notably, IL-33 increase is linked to decreased tumor size, while IL-18 and IL-6 are elevated post-treatment with a correlation to extracellular vesicle (EV) markers. Additionally, it explores the relationship between EV and checkpoint cytokines, noting correlations with markers like Tim-3 and static levels of CTLA-4 and PD-1, with...