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Systemic screening is crucial as paediatric cataracts may indicate underlying systemic diseases. The PECARE study analyzed 872 children, revealing that 15.1% had systemic disorders, with bilateral cases showing a significantly higher rate of 27.6% compared to 4.3% for unilateral cases. The findings highlight the need for thorough evaluations, especially for unilateral cataracts, and emphasize the importance of establishing a national consensus on genetic screening to address undiagnosed...