Evaluating SARS-CoV-2 VLP Vaccine Safety with Zebrafish

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This study emphasizes the importance of vaccine safety using the zebrafish larvae model. Focused on a SARS-CoV-2 Virus-Like Particle (VLP) vaccine, it investigates preclinical efficacy using zebrafish exposed via bath immersion to varying VLP concentrations. The study assessed criteria such as survival, morphology, and cardiovascular health, finding 100% survival without morphological abnormalities and successful vaccine uptake near the swim bladder. Conclusively, it demonstrates no...