Flow Cytometry Analysis of T-Cell Responses in PARP-Inhibited Tumours

This presentation explores the integration of flow cytometry in evaluating the synergy between T-cells and cancer cells to enhance immunotherapy efficacy. It delves into the tumour microenvironment with PARP inhibitors, highlighting their mechanisms such as DNA repair inhibition and activation of the cGAS-STING pathway. Methodologies include developing organoid co-cultures and optimising experimental protocols for precise T-cell analysis. Future directions aim to characterise cellular...