🧬 Hematopoiesis & Red Bone Marrow "Hematopoiesis is the process by which all blood cells are produced from pluripotent hematopoietic stem cells in the red bone marrow." All Blood Cell Types: Originate from a single pluripotent stem cell (hemocytoblast) derived from mesenchyme. Red Bone Marrow: The primary site of hematopoiesis in adults — a specialized microenvironment of hematopoietic, stromal, and vascular structures