Introduction to PhD Thesis Defense Presentation

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This presentation provides an in-depth exploration of the global impact of diseases and the role of methotrexate (MTX), focusing on the necessity for alternative solutions. Starting with the multifaceted uses of MTX- from high-dose applications in cancer treatment to lower doses in managing autoimmune diseases- the discussion highlights its mechanisms and the challenges posed by MTX-induced toxicity. By examining investigational agents like Ambrisentan, Agmatine, and Pirfenidone, the study...