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This lecture provides an in-depth exploration of Status Epilepticus (SE), focusing on its definition, importance, and the challenges in treatment. It delves into mammalian models, including chemical and electrical induction methods, and large animal studies, assessing their features and benefits. Key factors influencing model outcomes, such as genetic predispositions, environmental impacts, and epigenetics, are examined. Applications of rodent models in studying pathophysiology, treatment...