IDENTIFICATION OF NOVEL SCFVS AGAINST IMMUNE CHECKPOINT RECEPTORS.

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This research explores single-chain variable fragment (scFv) antibodies targeting checkpoint receptors, utilizing techniques such as phage display, cloning, and ELISA to develop a comprehensive workflow for therapeutic characterization. The dissertation details the methodology involving antibody library creation, bio-panning, and ELISA screening, with significant findings on scFv expression and potential advancements in cancer immunotherapy. The work underscores the therapeutic promise of...