Semaglutide's Impact on Vision Health

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This study explores the association between Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) and Semaglutide exposure, framing a clinical question within a defined cohort. It outlines methods for population definition, exposure, and outcomes, illustrated with a cohort-flow diagram. Results focus on interpreting the NAION association while balancing signal, confounding, and causality, ultimately providing actionable insights for monitoring and counseling.