Molecular Engineering of Pharmacological Policetides

This lecture explores polyketides, highlighting their chemical diversity and therapeutic potential. It covers PKS types, their enzymatic systems, and structural diversity with examples like macrolides, aromatic polyketides, and ionophores. Optimization techniques, including semisynthesis and synthetic biology, are discussed alongside clinical advancements. Applications in pharmaceutical, agricultural, and veterinary sectors are explored, with insights into future perspectives and the...