Impact of Stereotactic vs. HA-WBR on Brain Metastases

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This study addresses the challenges of radiation therapy for brain metastases in the USA, focusing on comparing Stereotactic Radiation (SR) and hippocampal-avoidant whole-brain radiation therapy (HA-WBR). Conducted as a Phase 3, open-label trial with 196 patients across four US centers, the research evaluates symptom severity and quality of life impacts for 5-20 metastasis cases. Findings suggest that SR improves MDASI-BT symptom scores and overall quality of life, while HA-WBR increases...