Journal club presentation from paper
Journal club presentation from paper
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This study on Bipolar Disorder (BPD) highlights the significance of a recent Nature Genetics publication, detailing the clinical burden and prevalence of BPD. It contrasts findings from 13,024 cases with previous null GWAS, revealing 11 genome-wide significant loci, including notable signals from FOXP2 and SGCD. The research quantifies SNP heritability at 17.3% and connects BPD liability to various phenotypes, particularly PTSD, depression, and ADHD. The performance of polygenic scores...