create 15 slide journal club presentation
create 15 slide journal club presentation
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Finerenone is a nonsteroidal mineralocorticoid receptor antagonist designed to mitigate kidney injury, particularly in diabetic chronic kidney disease (CKD), where previous trials have shown benefits. CKD affects about 9.1% of the global population, increasing risks for kidney and cardiovascular issues, with existing treatments like ACE inhibitors and ARBs not fully addressing these risks. Finerenone's mechanism targets MR activation, which leads to fibrosis, offering improved selectivity for...