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This presentation explores acute gastrointestinal graft-versus-host disease (aGVHD), a significant challenge in allo-HCT patients, particularly in steroid-refractory cases. We delve into the pathophysiology of GI aGVHD, highlighting the pivotal role of the intestinal tract and the associated inflammation and barrier dysfunction. The focus shifts to innovative regenerative strategies over traditional suppressive methods and the critical role of GLP-2 in intestinal repair. Advancements in GLP-2...