Differentiating Genitourinary Syndrome and Lichen Sclerosis

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This clinical case discusses a 55-year-old woman experiencing dyspareunia and itching, highlighting the differences between Genitourinary Syndrome of Menopause (GSM) and Lichen Sclerosis. Key diagnostic distinctions include tissue involvement patterns, with anal sparing indicating GSM. The correct diagnosis emphasizes periurethral and vaginal involvement, as both conditions share symptoms like pruritus and narrowing, driven by low estrogen levels leading to atrophy and altered vaginal flora.