Create a methods and materials slides for my presentation for SABI, a radiology conference for advanced body imaging. This is what I wrote: This IRB-approved retrospective study analyzed 79 liver lesions treated with histotripsy. [ml1.1]Pre-procedural CEUS was performed in 19 lesions. Microbubbles were administered to improve lesion conspicuity, with histotripsy performed 20 minutes later. Baseline tumor size, histology, treatment voltage, and duration were recorded. Prescribed ablation volumes were derived from device parameters using an ellipsoidal model; actual ablation volumes were measured on immediate post-treatment contrast-enhanced CT. The primary endpoint was the absolute difference between calculated and prescribed ablation volume. Between-group comparisons used Mann-Whitney U tests, within-group deviation was assessed by Wilcoxon signed-rank tests, and multivariate linear regression evaluated independent predictors of volume deviation.
Create a methods and materials slides for my presentation for SABI, a radiology conference for advanced body imaging. This is what I wrote: This IRB-approved retrospective study analyzed 79 liver lesions treated with histotripsy. [ml1.1]Pre-procedural CEUS was performed in 19 lesions. Microbubbles were administered to improve lesion conspicuity, with histotripsy performed 20 minutes later. Baseline tumor size, histology, treatment voltage, and duration were recorded. Prescribed ablation volumes were derived from device parameters using an ellipsoidal model; actual ablation volumes were measured on immediate post-treatment contrast-enhanced CT. The primary endpoint was the absolute difference between calculated and prescribed ablation volume. Between-group comparisons used Mann-Whitney U tests, within-group deviation was assessed by Wilcoxon signed-rank tests, and multivariate linear regression evaluated independent predictors of volume deviation.
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This study involves an IRB-approved retrospective analysis of 79 lesions, utilizing pre-procedural contrast-enhanced ultrasound (CEUS) for 19 lesions. Key parameters such as size, histology, voltage, and duration are meticulously recorded. Volume assessment employs a device-based ellipsoidal model to compare prescribed and post-treatment CT volumes, with statistical analysis conducted through nonparametric tests and multivariate regression to ensure robust findings.