Metabolic Reprogramming in Cancer: Pathways and Therapies

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This presentation delves into metabolic reprogramming, a pivotal concept in cancer biology. It begins by defining metabolic reprogramming and highlighting its significance in understanding cancer. Key concepts such as the Warburg effect, glycolysis, and the TCA cycle are examined, along with their pathways. The discussion progresses to regulatory mechanisms involving HIF1α, p53, c-Myc, and the PI3K/Akt pathway, emphasising tumour microenvironment interactions. Therapeutically, it explores...