need to include aim, method, result, explanation of each figure

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This study investigates the variant-specific ubiquitination by RNF168, focusing on how acidic patches define ubiquitination zones. It explores the recruitment of reader proteins to ubiquitinated variants at replication forks, utilizing binding measurements of key proteins. Additionally, it establishes a causal model for ubiquitination-dependent fork protection, employing various experimental methods to differentiate mH2A1.2 loading from signaling pathways. The findings contribute to...