presentation of de-escalation of care in breast cancer talking about neoadjuavnt chemotherapy in her22 positive cancer , new advances strating with case secanrio 42 year old ER PR positive her2 positive
presentation of de-escalation of care in breast cancer talking about neoadjuavnt chemotherapy in her22 positive cancer , new advances strating with case secanrio 42 year old ER PR positive her2 positive
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This case scenario focuses on reframing neoadjuvant care for a 42-year-old patient with ER/PR-positive, HER2-positive breast cancer. It emphasizes the importance of defining the cancer stage, anatomy, comorbidities, and patient goals, alongside baseline imaging and assessments. The discussion includes evidence for response-adapted de-escalation, utilizing pCR as a biomarker, and insights from studies like DESTINY-Breast11 and PHERGain. Finally, it highlights the application of these advances...