create a ppt of esophageal cancer the diagnosis and therapy: Here is the English translation: Péter Szabó is a 61-year-old accountant. He has a 20-year history of gastroesophageal reflux disease, for which he takes proton pump inhibitors irregularly. He is overweight, with a body mass index of 33 kg/m². He is a smoker and rarely consumes alcohol. Over the past three months, he has noticed progressively worsening dysphagia, initially limited to solid foods, but later extending to puréed foods as well. He has lost 8 kilograms. Physical examination is essentially unremarkable; no cervical lymphadenopathy is palpable. Laboratory tests reveal mild anemia. **Final diagnosis provided for Part II of the project:** * Distal esophageal adenocarcinoma * cT3N1M0 * HER2-negative * PD-L1 CPS 12 * MMR proficient **The "twist":** The patient is potentially curable. The multidisciplinary team (MDT) is planning an esophagectomy following neoadjuvant chemoradiotherapy. Students should compare the considerations betwee
create a ppt of esophageal cancer the diagnosis and therapy: Here is the English translation: Péter Szabó is a 61-year-old accountant. He has a 20-year history of gastroesophageal reflux disease, for which he takes proton pump inhibitors irregularly. He is overweight, with a body mass index of 33 kg/m². He is a smoker and rarely consumes alcohol. Over the past three months, he has noticed progressively worsening dysphagia, initially limited to solid foods, but later extending to puréed foods as well. He has lost 8 kilograms. Physical examination is essentially unremarkable; no cervical lymphadenopathy is palpable. Laboratory tests reveal mild anemia. **Final diagnosis provided for Part II of the project:** * Distal esophageal adenocarcinoma * cT3N1M0 * HER2-negative * PD-L1 CPS 12 * MMR proficient **The "twist":** The patient is potentially curable. The multidisciplinary team (MDT) is planning an esophagectomy following neoadjuvant chemoradiotherapy. Students should compare the considerations betwee
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This guide outlines the essential steps in managing curable cancer, starting with recognizing and staging the disease through a case study of dysphagia linked to adenocarcinoma. It emphasizes the importance of a multidisciplinary team to compare treatment strategies like CROSS chemoradiotherapy and FLOT. Finally, it highlights the need for thorough evaluation before esophagectomy to ensure optimal long-term outcomes, focusing on achieving R0 resection and reviewing pathology results.