OXIDATIVE STRESS AND IT'S ROLE IN NEURODEGENERATION

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This lecture on oxidative stress delves into its historical context, biochemistry, and the damage mechanisms that contribute to neurodegenerative diseases like Alzheimer's, Parkinson's, Huntington's, and ALS. We explore the imbalance of reactive oxygen and nitrogen species (ROS/RNS), mitochondrial dysfunction, and protein aggregation, providing insights into specific disease pathways. Additionally, we address therapeutic strategies, including antioxidants and emerging treatments. The...