Calcium Pyrophosphate Deposition Disease: Clinical and Educational Insights

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This lecture explores CPPD disease, an arthritis caused by CPP crystal deposition in joints, linked to cartilage degradation and risk factors like ageing. It covers clinical symptoms, ranging from acute inflammation to chronic flares, and axial involvement. Pathophysiology focuses on crystal deposition, NLRP3 inflammasome activation, and genetic influences. Diagnosis is detailed, highlighting synovial fluid analysis and imaging, with management targeting inflammation. The lecture concludes...