PK PD and DDD in rational use of antibiotics

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Delve into the critical interplay of Pharmacokinetics (PK) and Pharmacodynamics (PD) in the realm of antibiotic therapy, particularly within Intensive Care Units (ICUs). This keynote highlights essential PK/PD parameters such as volume of distribution, clearance, and half-life, and their implications on dosing efficacy. Understand the mechanisms of antibiotic action, emphasizing concentration and time-dependent effects relevant to aminoglycosides and β-lactams. Address antibiotic resistance...