Voxel-less Optimization in Tomotherapy

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Explore the innovative its of Volumetric Layer Optimization (VoLO) in radiotherapy as a transformative advancement over traditional voxel-based methods. VoLO addresses issues like computational expense and matrix complexity using reduced-dimensional surrogates and Principal Component Analysis. Learn how optimization algorithms such as the L-BFGS-B method enhance efficiency in fluence pattern optimization. With dynamic dose computation using ray tracing and collapsed cone methods, VoLO enables...