Autophagosome Formation: Roles of ATG9A and ATG2A

This research explores autophagosome formation, focusing on the roles of ATG9A and ATG2A in forming a heterotetrameric complex. It delves into the structural and functional aspects using experimental techniques to map interactions and assess mutational impacts. Insights into autophagic flux and lipid transfer mechanisms are discussed, highlighting critical findings and their broader implications in cellular biology.